Oprirea brusca a acestui tratament poate duce la aparitia sindromului de abstinenta. Acesta apare in cateva ore sau in cateva zile si consta in manifestari cum sunt anxietate marcata, insomnie, dureri musculare, dar se pot observa si agitatie, iritabilitate, dureri de cap, amorteli sau furnicaturi la nivelul extremitatilor, sensibilitate anormala l
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